Atopic Dermatitis

We are dedicated to providing relief to people living with the burden of atopic dermatitis.

Atopic dermatitis is the most common and severe form of eczema, a chronic inflammatory condition that can present as early as childhood and continue into adulthood. A moderate-to-severe form of the disease is characterized by rashes on the skin that often cover much of the body and can include intense, persistent itching, redness, cracking, and dryness.

While the exact cause of atopic dermatitis is unknown, the condition is often associated with a malfunctioning immune system. This malfunction can lead to inflamed skin, even in the absence of a major infection. Most people who develop the skin condition appear to have a family history (genetic factors) and are generally more susceptible to certain allergens in the environment.1

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Affecting millions of people, this skin condition often has a negative impact on overall quality of life.

Atopic dermatitis affects approximately 33 million people in the U.S.2 Despite recent promising advances, due to the difficult-to-treat nature of the condition, additional treatment options are still necessary.

Atopic dermatitis has a profound and negative impact on patients’ mental and physical functioning, limiting their activities and health-related quality of life. The severe scratching and itching associated with atopic dermatitis can severely affect sleep and negatively impact quality of life in adults.3 People with moderate-to-severe atopic dermatitis have reported a significant impact on quality of life that is similar to those patients living with psoriasis.4

References:

  1. National Institute of Arthritis and Musculoskeletal and Skin Diseases. Atopic Dermatitis. https://www.niams.nih.gov/Health_Info/Atopic_Dermatitis/default.asp#d. Accessed August 29, 2017.
  2. Silverberg JI, Hanifin JM. Adult eczema prevalence and associations with asthma and other health and demographic factors: a US population-based study. J Allergy Clin Immunol. 2013;132(5):1132-8.
  3. Jeon C, Yan D. Frequency and management of sleep disturbance in adults with atopic dermatitis: A systematic review. Dermatol Ther. 2017;7:349–364.
  4. Carroll CL, Balkrishnan R, Feldman SR, Fleischer AB Jr, Manuel JC.. The burden of atopic dermatitis: Impact on the patient, family, and society. The burden of atopic dermatitis: impact on the patient, family, and society. Pediatric Dermatol. 2005;22:192-199.